Annual report pursuant to Section 13 and 15(d)

Stock options and warrants (Schedule of Stock-based Compensation) (Details)

v2.4.0.8
Stock options and warrants (Schedule of Stock-based Compensation) (Details) (USD $)
 12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Share-based compensation, operating expense $ 1,437,865 $ 901,161 $ 1,336,177
Employees, officers, and directors [Member]
      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Share-based compensation, operating expense 1,436,572 833,351 1,200,118
Investor relations services [Member]
      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Share-based compensation, operating expense    23,598 57,309
APPY1 activities [Member]
      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Share-based compensation, operating expense 1,293 38,460 54,304
Animal health activities [Member]
      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Share-based compensation, operating expense    5,752 24,446
Selling, general and administrative expenses [Member]
      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Share-based compensation, operating expense 1,298,942 862,701 1,281,873
Research and development expenses [Member]
      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Share-based compensation, operating expense $ 138,923 $ 38,460 $ 54,304