Quarterly report pursuant to Section 13 or 15(d)

Property and equipment (Details)

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Property and equipment (Details) (USD $)
3 Months Ended 9 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Sep. 30, 2013
Sep. 30, 2012
Dec. 31, 2012
Property, Plant and Equipment [Line Items]          
Property and equipment $ 5,583,139   $ 5,583,139   $ 5,562,898
Less accumulated depreciation 3,264,072   3,264,072   3,078,359
Total property and equipment, net 2,319,067   2,319,067   2,484,539
Depreciation expense 59,000 91,000 190,000 277,000  
Land and improvements [Member]
         
Property, Plant and Equipment [Line Items]          
Property and equipment 1,107,508   1,107,508   1,107,508
Building [Member]
         
Property, Plant and Equipment [Line Items]          
Property and equipment 2,589,231   2,589,231   2,589,231
Building improvements [Member]
         
Property, Plant and Equipment [Line Items]          
Property and equipment 253,526   253,526   251,049
Laboratory equipment [Member]
         
Property, Plant and Equipment [Line Items]          
Property and equipment 1,220,735   1,220,735   1,211,418
Office and computer equipment [Member]
         
Property, Plant and Equipment [Line Items]          
Property and equipment $ 412,139   $ 412,139   $ 403,692